Characterization of reduced graphene oxide field-effect transistor and its application to biosensor

摘要

We confirmed the specific detection of immunoglobulin E (IgE) using an aptamer-immobilized reduced graphene oxide (rGO) field effect transistor (FET). The detection limit and dynamic range were estimated to be 8.1 ng/ml and 10~4, respectively. These characteristics are comparable with these of current fluorescent markers. Although the mobility of rGO-FET was around 6cm~2V~(-1) s~(-1), which is two to three orders lower than that of mechanically exfoliated pristine graphene FET, its sensitivity to IgE was only one order lower than that of pristine graphene FET.