A Quasi Species of the pre-S/S Gene and Mutations of Enhancer II/Core Promoter/pre-C in Mothers and Their Children Infected with Hepatitis B Virus via Mother-to-Infant Transmission

摘要

BackgroundHepatitis B virus (HBV) infection has a tendency to be chronic. The quasi species of HBV in the pre-S/S gene and mutations in enhancer II (EnhII)/core promoter (CP)/pre-C of HBV were studied in asymptomatic carrier (AsC) mothers and their children with different virus loads, to gain a better understanding of the pathogenic mechanisms of HBV