Both CD31+ and CD31- Naive CD4+ T Cells Are Persistent HIV Type 1-Infected Reservoirs in Individuals Receiving Antiretroviral Therapy

Fiona Wightman; Ajantha Solomon; Gabriela Khoury; Justin A. Green; Lachlan Gray; Paul R. Gorry; Yung Shwen Ho; Nitin K. Saksena; Jennifer Hoy; Suzanne M. Crowe; Paul U. Cameron

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Both CD31+ and CD31- Naive CD4+ T Cells Are Persistent HIV Type 1-Infected Reservoirs in Individuals Receiving Antiretroviral Therapy

机译：CD31 + 和CD31 -幼稚CD4 + T细胞在接受抗逆转录病毒治疗的个体中都是持久性HIV 1型感染的储库

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Background. Naive T cell recovery is critical for successful immune reconstitution after antiretroviral therapy (ART), but the relative contribution of CD31+ and CD31- naive T cells to immune reconstitution and viral persistence is unknown.

机译：背景。幼稚T细胞的恢复对于抗逆转录病毒疗法（ART）成功免疫重建至关重要，但是CD31 + 和CD31 -幼稚T细胞对免疫重建和病毒持久性的相对贡献未知。

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《Journal of Infectious Diseases》 |2010年第11期|p.1738-1748|共11页
作者
Fiona Wightman; Ajantha Solomon; Gabriela Khoury; Justin A. Green; Lachlan Gray; Paul R. Gorry; Yung Shwen Ho; Nitin K. Saksena; Jennifer Hoy; Suzanne M. Crowe; Paul U. Cameron;
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Department of Medicine, Monash University;

Department of Medicine, Monash University;

Department of Medicine, Monash University;

Department of Infectious Diseases and Immunity, Imperial College, Hammersmith Campus, London, United Kingdom;

Centre for Virology, Burnet Institute|Department of Microbiology and Immunology, University of Melbourne;

Department of Medicine, Monash University|Centre for Virology, Burnet Institute|Department of Microbiology and Immunology, University of Melbourne;

Retroviral Genetics Division, Center for Virus Research, Westmead Millennium Institute, Westmead, New South Wales, Australia;

Retroviral Genetics Division, Center for Virus Research, Westmead Millennium Institute, Westmead, New South Wales, Australia;

Department of Medicine, Monash University|Infectious Diseases Unit, Alfred Hospital, Melbourne;

Department of Medicine, Monash University|Centre for Virology, B;

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1. Both CD31(+) and CD31 naive CD4(+) T cells are persistent HIV type 1-infected reservoirs in individuals receiving antiretroviral therapy. [J] . Wightman F, Solomon A, Khoury G, The Journal of Infectious Diseases . 2010,第11期

机译：在接受抗逆转录病毒治疗的个体中，CD31（+）和CD31幼稚CD4（+）T细胞都是感染了HIV 1型的持久性水库。
2. Relationship between the size of the human immunodeficiency virus type 1 (HIV-1) reservoir in peripheral blood CD4+ T cells and CD4+:CD8+ T cell ratios in aviremic HIV-1-infected individuals receiving long-term highly active antiretroviral therapy. [J] . Chun TW, Justement JS, Pandya P, The Journal of Infectious Diseases . 2002,第11期

机译：接受长期高效抗逆转录病毒治疗的非HIV-1感染个体中，外周血CD4 + T细胞中人类免疫缺陷病毒1型（HIV-1）库的大小与CD4 +：CD8 + T细胞比率之间的关系。
3. CD4+ T cell count recovery in HIV type 1-infected patients is independent of class of antiretroviral therapy. [J] . Khanna N, Opravil M, Furrer H, Clinical infectious diseases . 2008,第8期

机译：HIV 1型感染患者的CD4 + T细胞计数恢复与抗逆转录病毒疗法的类别无关。
4. A Mathematical Model of Antiretroviral Therapy Evaluation for HIV Type [C] . Silvia Martorano Raimundo, Ezio Venturino, Hyun Mo Yang International Conference on Numerical Analysis and Applied Mathematics . 2009

机译：艾滋病毒型抗逆转录病毒治疗评价的数学模型
5. CD4+ T Cell Recovery and Cerebrospinal Fluid Escape After Antiretroviral Therapy Initiation in Acute HIV-1 Infection [D] . ?Handoko, Ryan Christopher 2020

机译：CD4 + T 细胞回收和急性 HIV-1 感染脑脊液逃逸抗逆转录病毒疗法开始后
6. Chimeric Antigen Receptor T Cells Guided by the Single-Chain Fv of a Broadly Neutralizing Antibody Specifically and Effectively Eradicate Virus Reactivated from Latency in CD4+ T Lymphocytes Isolated from HIV-1-Infected Individuals Receiving Suppressive Combined Antiretroviral Therapy [O] . Bingfeng Liu, Fan Zou, Lijuan Lu, 2016

机译：嵌合抗原受体T细胞指导的广泛中和抗体的单链Fv特异性和有效地根除从接受HIV-1感染的个体接受抑制性联合抗逆转录病毒疗法的CD4 + T淋巴细胞中的潜伏期重新激活的病毒。
7. Both CD31+and CD31−Naive CD4+T Cells Are Persistent HIV Type 1–Infected Reservoirs in Individuals Receiving Antiretroviral Therapy [O] . Fiona Wightman, Ajantha Solomon, Gabriela Khoury, 2010

机译：CD31 +和CD31-NaiveCD4 + T细胞都是接受抗逆转录病毒治疗的个体中持久的HIV型1感染储层

Both CD31+ and CD31- Naive CD4+ T Cells Are Persistent HIV Type 1-Infected Reservoirs in Individuals Receiving Antiretroviral Therapy

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