An Ad5-Vectored HIV-1 Vaccine Elicits Cell-mediated Immunity but does not Affect Disease Progression in HIV-1–infected Male Subjects: Results From a Randomized Placebo-Controlled Trial (The Step Study)

D. W. Fitzgerald; H. Janes; M. Robertson; R. Coombs; I. Frank; P. Gilbert; M. Loufty; D. Mehrotra

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An Ad5-Vectored HIV-1 Vaccine Elicits Cell-mediated Immunity but does not Affect Disease Progression in HIV-1–infected Male Subjects: Results From a Randomized Placebo-Controlled Trial (The Step Study)

机译：Ad5载体的HIV-1疫苗可激发细胞介导的免疫力，但不影响HIV-1感染的男性受试者的疾病进展：随机安慰剂对照试验的结果（分步研究）

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(See the editorial commentary by Altfeld and Goulder, on pages 753–5.)

机译：（请参阅第753-5页的Altfeld和Goulder的社论评论。）

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《Journal of Infectious Diseases》 |2011年第6期|p.765-772|共8页
作者
D. W. Fitzgerald; H. Janes; M. Robertson; R. Coombs; I. Frank; P. Gilbert; M. Loufty; D. Mehrotra;
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Center for Global Health, Weill Cornell Medical College, New York, New York;

Fred Hutchinson Cancer Research Center, Seattle, Washington;

Merck Research Laboratories, North Wales, Pennsylvania;

Departments of Laboratory Medicine & Medicine, University of Washington, Seattle;

Department of Medicine, University of Pennsylvania, Philadelphia;

Fred Hutchinson Cancer Research Center, Seattle, Washington;

Mona Loufty, Department of Medicine, University of Toronto, Canada;

Merck Research Laboratories, North Wales, Pennsylvania;

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1. An Ad5-vectored HIV-1 vaccine elicits cell-mediated immunity but does not affect disease progression in HIV-1-infected male subjects: results from a randomized placebo-controlled trial (the Step study). [J] . Fitzgerald DW, Janes H, Robertson M, The Journal of Infectious Diseases . 2011,第6期

机译：用Ad5介导的HIV-1疫苗可引发细胞介导的免疫，但不影响感染HIV-1的男性受试者的疾病进展：一项来自随机安慰剂对照试验的结果（该步骤研究）。
2. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial. [J] . Buchbinder SP, Mehrotra DV, Duerr A, The Lancet . 2008,第9653期

机译：细胞介导的HIV-1疫苗免疫效果评估（分步研究）：一项双盲，随机，安慰剂对照，概念测试的试验。
3. Daily aciclovir for HIV-1 disease progression in people dually infected with HIV-1 and herpes simplex virus type 2: a randomised placebo-controlled trial. [J] . Lingappa JR, Baeten JM, Wald The Lancet . 2010,第9717期

机译：在双重感染了HIV-1和单纯疱疹病毒2型的人中，每日aciclovir用于HIV-1疾病进展的随机安慰剂对照试验。
4. Transmissibility and Disease Progression in Groups of Individuals Infected with Different HIV-1 Subtypes in Cuba [C] . H.M. Diaz, A.L. Lubian, M. Blanco International AIDS Conference . 2004

机译：在古巴的不同HIV-1亚型感染的个体中的传染性和疾病进展
5. A model of HIV-1 disease progression and treatment: The subclass of latently infected CD4+ T cells becomes undetectable when both IL-2 and HAART are used. [D] . O'Hara, Karen Ann Bradford. 2002

机译：HIV-1疾病进展和治疗的模型：当同时使用IL-2和HAART时，无法检测到潜在感染的CD4 + T细胞的亚类。
6. An Ad5-Vectored HIV-1 Vaccine Elicits Cell-mediated Immunity but does not Affect Disease Progression in HIV-1–infected Male Subjects: Results From a Randomized Placebo-Controlled Trial (The Step Study) [O] . D. W. Fitzgerald, H. Janes, M. Robertson, -1

机译：Ad5载体的HIV-1疫苗可激发细胞介导的免疫力但不影响HIV-1感染的男性受试者的疾病进展：随机安慰剂对照试验的结果（分步研究）
7. An Ad5-Vectored HIV-1 Vaccine Elicits Cell-mediated Immunity but does not Affect Disease Progression in HIV-1–infected Male Subjects: Results From a Randomized Placebo-Controlled Trial (The Step Study) [O] . Fitzgerald, D. W., Janes, H., Robertson, M., 2011

机译：Ad5载体的HIV-1疫苗可激发细胞介导的免疫力，但不影响HIV-1感染的男性受试者的疾病进展：随机安慰剂对照试验的结果（分步研究）

An Ad5-Vectored HIV-1 Vaccine Elicits Cell-mediated Immunity but does not Affect Disease Progression in HIV-1–infected Male Subjects: Results From a Randomized Placebo-Controlled Trial (The Step Study)

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