Contact and contactless diffuse reflectance spectroscopy: potential for recovery monitoring of vascular lesions after intense pulsed light treatment

摘要

Optical fiber contact probe diffuse reflectancenspectroscopy and remote multispectral imaging methods innthe spectral range of 400 to 1100 nm were used for skinnvascular malformation assessment and recovery tracing af-nter treatment by intense pulsed light. The results confirmednthat oxy-hemoglobin relative changes and the optical den-nsity difference between lesion and healthy skin in the spec-ntral region 500 to 600 nm may be successfully used fornobjective appraisal of the therapy effect. Color redness pa-nrameter a* = 2 is suggested as a diagnostic border to distin-nguish healthy skin and vascular lesions, and as the indicatornof phototreatment efficiency. Valuable diagnostic informa-ntion on large area (>5 mm) lesions and lesions with un-ncertain borders can be proved by the multispectral imagingnmethod