A Task for Democracy

摘要

Over the past decade, a tool has emerged that enables very precise editing of the human genome, bringing with it tremendous value for research. Yet this gene-editing tool, called CRISPR, also generates worries that society may not be able to control its use and that it may deliver significant harm by allowing scientists to reshape the very basis of life. The tool, which enables scientists to inexpensively manipulate targeted bits of genetic code with relative accuracy, could have a broad range of applications. These uses include treating human genetic disorders, breeding new plants and animals, and controlling disease-carrying insects or invasive species. A Crack in Creation tells the story of this revolutionary technology from the perspective of biochemist Jennifer Doudna and one of her former graduate students, Samuel Sternberg, who were central figures in the technology's development.