Role of residual vitreous cortex removal in prevention of postoperative vitreous hemorrhage in diabetic vitrectomy

摘要

Aim To evaluate whether residual vitreous cortex removal has a role in the prevention of postoperative vitreous hemorrhage in diabetic vitrectomy. Methods Retrospective, comparative, nonrandomized study on a consecutive series of patients who underwent vitrectomy for diabetic eye disease. Recurrence of postoperative vitreous hemorrhage was compared in patients following surgery with and without residual vitreous cortex removal. Results During the study period, 59 patients had vitrectomy for diabetic disease. In 31 patients (group 1), the residual vitreous cortex was not removed and in 28 patients (group 2) the residual vitreous cortex was removed during surgery. Both groups were matched for number of patients, age, sex, duration of follow-up, and diagnosis. Recurrent postoperative vitreous hemorrhage (RVH) was noted in ten patients in group 1 (10/31, 32.25%) and in two patients in group 2 (2/28, 7.14%). The difference in postoperative vitreous hemorrhage between the two groups was statistically significant (P = 0.017). Logistic regression analysis showed that residual vitreous cortex removal and presence of intravitreal gas tamponade were associated with reduced risk of postoperative vitreous hemorrhage. However, only residual vitreous cortex removal was statistically significant factor in reducing risk of postoperative vitreous hemorrhage [odds ratio = 0.174; confidence interval (CI) = 0.0331–0.919; P = 0.040]. Conclusion Residual vitreous cortex removal may be beneficial in reducing recurrence of postoperative vitreous hemorrhage following diabetic vitrectomy. Further randomized studies should be performed to evaluate the potential of this surgical technique in preventing postoperative recurrent vitreous hemorrhage following diabetic vitrectomy.