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Numerical analysis of blood flow in realistic arteries subjected to strong non-uniform magnetic fields

机译:强不均匀磁场作用下真实动脉血流的数值分析

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The paper reports on a comprehensive mathematical model for simulations of blood flow under the presence of strong non-uniform magnetic fields. The model consists of a set of Navier-Stokes equations accounting for the Lorentz and magnetisation forces, and a simplified set of Maxwell's equations (Biot-Savart/Ampere's law) for treating the imposed magnetic fields. The relevant hydrodynamic and electromagnetic properties of human blood were taken from the literature. The model is then validated for different test cases ranging from a simple cylindrical geometry to real-life right-coronary arteries in humans. The time-dependency of the wall-shear-stress for different stenosis growth rates and the effects of the imposed strong non-uniform magnetic fields on the blood flow pattern are presented and analysed. It is concluded that an imposed non-uniform magnetic field can create significant changes in the secondary flow patterns, thus making it possible to use this technique for optimisations of targeted drug delivery.
机译:该论文报告了一种用于在强非均匀磁场存在下模拟血流的综合数学模型。该模型包括一组考虑了洛伦兹和磁化力的Navier-Stokes方程,以及一组简化的Maxwell方程组(Biot-Savart / Ampere定律),用于处理施加的磁场。人体血液的相关流体动力学和电磁特性均来自文献。然后针对不同的测试案例对模型进行验证,这些测试案例的范围从简单的圆柱几何到人类的现实生活中的右冠状动脉。提出并分析了不同的狭窄率下壁剪切应力的时间依赖性以及强非均匀磁场强加对血流模式的影响。结论是施加的不均匀磁场会在次级流动模式中产生重大变化,因此可以使用此技术优化靶向药物的输送。

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