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Professional Exposure To Biocides: A Comparison Of Human Exposure Models For Surface Disinfectants

机译:专业接触杀生物剂:表面消毒剂人类接触模型的比较

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摘要

The assessment of occupational exposure following disinfection of hard surfaces with a biocidal product based on didecyldimethylammonium chloride (DDAC) was carried out for both spraying and wiping-off applications. Several human exposure models were used, and the results were compared, in order to figure out the differences and identify the most representative model. No risk management measurements were considered. For dermal exposure, models produced similar results except for ConsExpo 4.1 ('instant application' mode) and RISKOFDERM for spraying and wiping. As regards inhalation exposure, only some models take the inhalation route into account. In these cases, levels proved to be negligible or to contribute to the total systemic dose by <12%. None of the investigated models could be concluded to be the best candidate for the assessment of professional exposure to hard surface disinfectants. This paper highlights the necessity of additional monitoring studies for the measurement of the actual exposure for the investigated scenarios.
机译:对于喷涂和擦拭应用,均使用基于二癸基二甲基氯化铵(DDAC)的杀生物产品对硬表面进行消毒后,对职业接触进行了评估。使用了几种人体暴露模型,并对结果进行了比较,以找出差异并确定最具代表性的模型。没有考虑风险管理措施。对于皮肤暴露,除了ConsExpo 4.1(“即时施用”模式)和用于喷涂和擦拭的RISKOFDERM,模型产生的结果相似。关于吸入暴露,只有某些模型考虑了吸入途径。在这些情况下,水平可忽略不计或对全身总剂量的贡献小于12%。没有一个被调查的模型可以被认为是评估专业接触硬表面消毒剂的最佳人选。本文强调了需要进行额外的监测研究,以测量所研究情景的实际暴露量。

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