A calibration-free method for measurement of sound speed in biological tissue samples

摘要

A transmission method for speed-of-sound measurement in biological tissue specimens is described. The technique involves detecting the time of arrival of a transmitted pulse with a small hydrophone that penetrates the tissue sample in accurately known increments. The technique allows localized measurements to be made without the error-prone task of measuring the thickness of the specimen and without calibration of the apparatus in a reference medium with known speed of sound.