A 1.2nW Analog Electrocardiogram Processor Achieving a 99.63% QRS Complex Detection Sensitivity

摘要

An energy-efficient electrocardiogram (ECG) processor for real-time QRS detection is presented. The proposed algorithm is based on the Pan-Tompkins algorithm and it is implemented in the analog domain leveraging ultra-low power analog electronics biased in subthreshold. Operational transconductance amplifiers with similar to 100 mV linear range are used in almost all of the processing blocks, while squaring is performed on current signals. Additionally, instead of adaptive thresholding, a fixed-level thresholding is performed, thereby eliminating the need for additional blocks such as memory and threshold update. The processor is designed in 65 nm TSMC CMOS technology and has a footprint of 0.078 mm(2). When supplied by a 1 V supply, the processor consumes 1.2 nW. Using the recordings in the MIT-BIH database, the processor achieves an average QRS detection sensitivity of 99.63% and positive predictivity of 99.47%.