Optical Doppler tomography

摘要

Optical Doppler tomography (ODT) is an imaging modality that takesnadvantage of the short coherence length of a broad-band light sources tonperform micrometer-scale, cross-sectional imaging of tissue structurenand blood flow dynamics simultaneously. The authors review in this papernthe principal of ODT and its applications. Results from in vitro and innvivo model studies demonstrated that ODT can map the blood flow velocitynprofile with high spatial resolution in scattering medium. ODT detectionnmechanisms are illustrated using Monte Carlo simulations. Thenapplication of ODT to image brain hemodynamics is demonstrated. Finally,nthe authors discuss the limitations of the current technology andnapplication of a phase resolved technique to improve image speed andnquality