A randomized trial to compare two dosing intervals of misoprostol following mifepristone administration in second trimester medical abortion

摘要

BACKGROUND The conventional timing of misoprostol administration after mifepristone for second trimester medical abortion is 36–48 h, but simultaneous administration, which may make the regimen more convenient, has not been studied. The objective of this randomized comparison study is to compare two intervals of administration of misoprostol after pretreatment with mifepristone for second trimester medical abortion.