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ESHRE PGD Consortium data collection XI: cycles from January to December 2008 with pregnancy follow-up to October 2009†

机译:ESHRE PGD协会数据收集十一:从2008年1月至12月的周期,以及对妊娠的随访,直至2009年10月。†

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摘要

The 11th report of the European Society of Human Reproduction and Embryology Preimplantation Genetic Diagnosis Consortium is presented, documenting cycles collected for the calendar year 2008 and follow-up of the pregnancies and babies born until October 2009 which resulted from these cycles. Since the beginning of the data collections, there has been a steady increase in the number of cycles, pregnancies and babies reported annually. For data collection XI, 53 centres have participated, reporting on 5641 cycles to oocyte retrieval (OR), along with details of the follow-up on 1418 pregnancies and 1169 babies born. A total of 774 OR were reported for chromosomal abnormalities, 96 OR for sexing for X-linked diseases, 1363 OR for monogenic diseases, 3401 OR for preimplantation genetic screening and 5 OR for social sexing. Data XI is compared with the cumulative data for data collections I–X.
机译:提出了欧洲人类生殖和胚胎学学会植入前遗传诊断协会的第11份报告,记录了2008日历年收集的周期以及这些周期导致的直到2009年10月的孕妇和婴儿的随访。自开始收集数据以来,每年报告的周期,妊娠和婴儿数量一直在稳定增长。对于数据收集XI,有53个中心参与,报告了卵母细胞检索(OR)的5641个周期,以及1418例妊娠和1169例婴儿的随访详情。染色体异常的报告总数为774 OR,X连锁疾病的性别报告为96 OR,单基因疾病的报告为1363 OR,植入前基因筛查的报告为3401 OR,社交性别的报告为5 OR。将数据XI与数据收集I–X的累积数据进行比较。

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  • 来源
    《Human Reproduction》 |2012年第7期|p.1887-1911|共25页
  • 作者单位

    1ESHRE Central Office, Meerstraat 60, 1852 Grimbergen, Belgium 2Laboratory of Medical Genetics, University of Athens, St. Sophia's Children's Hospital, 11527 Athens, Greece 3PGD Working Group Maastricht, Department of Clinical Genetics, Maastricht University Medical Centre, PO Box 5800, 6202 AZ Maastricht, The Netherlands 4Centre for Medical Genetics, UZ Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium 5Service de la Biologie de la Reproduction, SIHCUS-CMCO, 19, Rue Louis Pasteur, BP120, 67303 Schiltigheim, France 6Instituto Valenciano de Infertilidad, (IVI) Istanbul, Oya Sokak No: 23ª 34387 Mecidiyekoy, Istanbul, Turkey 7Reprogenetics, 3 Regent Street, Suite 301, Livingston, NJ 07039, USA;

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