Guidelines recommend epinephrine as the primary medical intervention for cardiac arrest. However, no randomized trial data are available to support this recommendation. In this observational study from the American Heart Association's Get With The Guidelines-Resuscitation multi-center registry of in-hospital cardiac arrest, the authors sought to determine if timing of epinephrine administration in the setting of non-shockable (i.e. pulseless electrical activity or asystole) in-hospital cardiac arrest is associated with patient outcomes. Among 25,095 patients with non-shockable in-hospital cardiac arrest, the median time to first epinephrine was 3 minutes (IQR 1-5 minutes).
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机译：指南建议肾上腺素作为心脏骤停的主要医学干预措施。但是，没有随机试验数据可支持该建议。在美国心脏协会的《 Get With the Guidelines-Resurcitation》多中心医院院内心脏骤停的观察性研究中，作者试图确定肾上腺素的给药时机是否处于不可电击（即无脉搏电活动或心搏停止）的环境中。院内心脏骤停与患者预后相关。在25,095例不可电击的院内心脏骤停患者中，首次肾上腺素的中位时间为3分钟（IQR 1-5分钟）。
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