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Automatic classifier based on heart rate variability to identify fallers among hypertensive subjects

机译:基于心率变异性的自动分类器,可识别高血压受试者中的跌倒者

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Accidental falls are a major problem of later life. Different technologies to predict falls have been investigated, but with limited success, mainly because of low specificity due to a high false positive rate. This Letter presents an automatic classifier based on heart rate variability (HRV) analysis with the goal to identify fallers automatically. HRV was used in this study as it is considered a good estimator of autonomic nervous system (ANS) states, which are responsible, among other things, for human balance control. Nominal 24 h electrocardiogram recordings from 168 cardiac patients (age 72 ± 8 years, 60 female), of which 47 were fallers, were investigated. Linear and nonlinear HRV properties were analysed in 30 min excerpts. Different data mining approaches were adopted and their performances were compared with a subject-based receiver operating characteristic analysis. The best performance was achieved by a hybrid algorithm, RUSBoost, integrated with feature selection method based on principal component analysis, which achieved satisfactory specificity and accuracy (80 and 72%, respectively), but low sensitivity (51%). These results suggested that ANS states causing falls could be reliably detected, but also that not all the falls were due to ANS states.
机译:意外跌倒是以后生活的主要问题。已经研究了多种预测跌倒的技术,但成功率有限,主要是因为假阳性率高,特异性低。这封信提出了一种基于心率变异性(HRV)分析的自动分类器,旨在自动识别跌倒者。在这项研究中使用了HRV,因为它被认为是自主神经系统(ANS)状态的良好估算器,它除其他因素外,还可以控制人体平衡。研究了来自168位心脏病患者(72±8岁,女性60位)的名义24小时心电图记录,其中47位是跌倒者。在30分钟的摘录中分析了线性和非线性HRV属性。采用了不同的数据挖掘方法,并将其性能与基于主题的接收器操作特性分析进行了比较。通过将混合算法RUSBoost与基于主成分分析的特征选择方法相集成,可以实现最佳性能,该方法具有令人满意的特异性和准确性(分别为80%和72%),但灵敏度较低(51%)。这些结果表明,引起跌倒的ANS状态可以被可靠地检测到,但是并非所有跌倒都是由ANS状态引起的。

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