Comparison of the efficacy and tolerability of preservative-free and preservative-containing formulations of the dorzolamide/timolol fixed combination (COSOPT™) in patients with elevated intraocular pressure in a randomized clinical trial

Arthur Shedden; Ingrid A. Adamsons; Albert J. Getson; Jean K. Laurence; Christopher R. Lines; David J. Hewitt; Tony W. Ho

首页> 外文期刊>Graefe's Archive for Clinical and Experimental Ophthalmology >Comparison of the efficacy and tolerability of preservative-free and preservative-containing formulations of the dorzolamide/timolol fixed combination (COSOPT™) in patients with elevated intraocular pressure in a randomized clinical trial

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Comparison of the efficacy and tolerability of preservative-free and preservative-containing formulations of the dorzolamide/timolol fixed combination (COSOPT™) in patients with elevated intraocular pressure in a randomized clinical trial

机译：在一项随机临床试验中比较多佐胺/替莫洛尔固定组合（COSOPT™）的无防腐剂和含防腐剂制剂的功效和耐受性

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Background The aim of this study was to compare the efficacy and tolerability of preservative-free (PF) and preservative-containing (PC) formulations of the dorzolamide/timolol fixed combination (COSOPT™) in patients with elevated intraocular pressure (IOP).

机译：背景技术这项研究的目的是比较多佐胺/替莫洛固定组合（COSOPT™）的无防腐剂（PF）和含防腐剂（PC）的制剂在眼内压升高（IOP）患者中的功效和耐受性。

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《Graefe's Archive for Clinical and Experimental Ophthalmology》 |2010年第12期|p.1757-1764|共8页
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Arthur Shedden; Ingrid A. Adamsons; Albert J. Getson; Jean K. Laurence; Christopher R. Lines; David J. Hewitt; Tony W. Ho;
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1. Comparison of the efficacy and tolerability of preservative-free and preservative-containing formulations of the dorzolamide/timolol fixed combination (COSOPT) in patients with elevated intraocular pressure in a randomized clinical trial. [J] . Shedden A, Adamsons IA, Getson AJ, Graefe's archive for clinical and experimental ophthalmology: Albrecht von Graefes Archiv fur klinische und experimentelle Opthalmologie . 2010,第12期

机译：在一项随机临床试验中比较多佐胺/替莫洛尔固定组合（COSOPT）的不含防腐剂和含防腐剂的制剂的功效和耐受性。
2. Additive intraocular pressure reduction effect of fixed combination of maleate timolol 0.5%/dorzolamide 2% (Cosopt) on monotherapy with latanoprost (Xalatan) in patients with elevated intraocular pressure: a prospective, 4-week, open-label, randomized, controlled clinical trial. [J] . Hatanaka M, Reis A, Sano ME, Journal of glaucoma . 2010,第5期

机译：马来酸替莫洛尔0.5％/多佐胺2％（Cosopt）固定组合对眼压升高的患者使用拉坦前列素（Xalatan）单药治疗的加减眼压效果：前瞻性，4周，开放标签，随机，对照临床试验。
3. Efficacy and tolerability of fixed combination of brimonidine 0.2%/timolol 0.5% compared with fixed combination of dorzolamide 2%/timolol 0.5% in the treatment of patients with elevated intraocular pressure: A meta-analysis of randomized controlled trials [J] . BudengeriP., ChengJ.-W., CaiJ.-P., Journal of ocular pharmacology and therapeutics: The official journal of the Association for Ocular Pharmacology and Therapeutics . 2013,第5期

机译：固定剂量溴莫尼定0.2％/噻吗洛尔0.5％与多佐胺2％/噻吗洛尔0.5％固定组合治疗高眼压的疗效和耐受性：一项随机对照试验的荟萃分析
4. Changes in Intraocular Pressure, Ocular Perfusion Pressure and Blood Flow Fluctuations during Dorzolamide vs Timolol Add-on Therapies in Glaucoma Patients Previously Treated with Prostaglandin Analogue [C] . Siaudvytyte L., Januleviciene I., Barsauskaite R., International Symposium on Ocular Pharmacology and Therapeutics . 2011

机译：含有前列腺素患者的多唑胺患者中的眼内压，眼灌注压力和血流波动的变化，前列腺素相似
5. Long-term comparison of bone regeneration between immediate and conventional loading of implants placed in fresh extracted sockets in periodontally compromised patients: 6-year randomized clinical trial. [D] . Alqahtani, Nabeeh Abdullah. 2014

机译：在牙周病患者中，在新鲜的拔牙窝中立即和常规负载的种植体之间进行骨再生的长期比较：6年随机临床试验。
6. Efficacy and Tolerability of the Fixed Combinations Latanoprost/Timolol versus Dorzolamide/Timolol in Patients with Elevated Intraocular Pressure: A Meta-Analysis of Randomized Controlled Trials [O] . Miao He, Wei Wang, Wenyong Huang -1

机译：固定剂量拉坦前列素/替莫洛与多佐胺/替莫洛联合治疗高眼压的疗效和耐受性：一项随机对照试验的荟萃分析
7. Efficacy and tolerability of the fixed combinations latanoprost/timolol versus dorzolamide/timolol in patients with elevated intraocular pressure: a meta-analysis of randomized controlled trials. [O] . Miao He, Wei Wang, Wenyong Huang 2013

机译：拉坦前列素/噻吗洛尔与多佐胺/噻吗洛尔固定组合在眼压升高患者中的疗效和耐受性：随机对照试验的荟萃分析。

Comparison of the efficacy and tolerability of preservative-free and preservative-containing formulations of the dorzolamide/timolol fixed combination (COSOPT™) in patients with elevated intraocular pressure in a randomized clinical trial

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