...
首页> 外文期刊>Global public health >Viral suppression among persons living with HIV in Trinidad & Tobago: Implications for targeted prevention programmes
【24h】

Viral suppression among persons living with HIV in Trinidad & Tobago: Implications for targeted prevention programmes

机译:特立尼达和多巴哥的艾滋病毒携带者中的病毒抑制:对有针对性的预防计划的影响

获取原文
获取原文并翻译 | 示例

摘要

In Trinidad and Tobago, despite persons living with HIV (PLHIV) having access to subsidised treatment and care, only 47% PLHIV attain viral suppression. The study assessed the role of individual-level factors on viral suppression among PLHIV in Trinidad and Tobago. Data from 9,629 PLHIV who attended an HIV clinic between 2016 and 2018 were analysed. Cases were aged >= 18 who met the CDC HIV case definition. Viral suppression defined as a viral load of <200 copies/ml at last assessment. The chi-square test of association determined statistically significant relationships between individual factors and viral suppression. Logistic regression was used to estimate odds ratios (OR) for viral suppression. PLHIV who were males (OR = 0.76, 95% CI 0.67-0.87), men who have sex with men (MSM) (OR = 0.82, 95% CI 0.67-0.99), single/unmarried (OR = 0.69, 95% CI 0.55-0.87), aged 18-24 years (OR = 0.66, 95% CI 0.49-0.89), aged 25-49 years (OR = 0.81, 95% CI 0.70-0.94) were less likely to achieve viral suppression. These study findings demonstrate that retention/adherence programmes must urgently identify and target vulnerable PLHIV populations in Trinidad and Tobago to improve viral suppression. Further research examining community and societal factors, such as stigma and discrimination, is warranted.
机译:在特立尼达和多巴哥,尽管艾滋病毒感染者(PLHIV)可以得到补贴的治疗和护理,但只有47%的PLHIV获得了病毒抑制。该研究评估了特立尼达和多巴哥的个人水平因素在艾滋病毒感染者中抑制病毒的作用。分析了2016年至2018年期间参加艾滋病诊所的9,629名艾滋病毒感染者的数据。符合CDC HIV病例定义的年龄≥18岁的病例。病毒抑制定义为在最后一次评估中病毒载量小于200拷贝/ ml。关联的卡方检验确定了个体因素与病毒抑制之间的统计学显着关系。使用Logistic回归估计病毒抑制的优势比(OR)。男性的PLHIV(OR = 0.76,95%CI 0.67-0.87),与男性发生性关系的男性(MSM)(OR = 0.82,95%CI 0.67-0.99),单身/未婚(OR = 0.69,95%CI 0.55-0.87),年龄18-24岁(OR = 0.66,95%CI 0.49-0.89),年龄25-49岁(OR = 0.81,95%CI 0.70-0.94)不太可能实现病毒抑制。这些研究结果表明,保留/坚持计划必须紧急确定和瞄准特立尼达和多巴哥的易感染PLHIV人群,以改善病毒抑制作用。值得进一步研究,以检查社区和社会因素,例如污名和歧视。

著录项

  • 来源
    《Global public health 》 |2019年第11期| 1569-1577| 共9页
  • 作者

  • 作者单位

    Med Res Fdn Trinidad & Tobago 7 Queens Pk East Port Of Spain Trinid & Tobago;

    Florida Int Univ Dept Epidemiol Robert Stempel Coll Publ Hlth & Social Work Miami FL 33199 USA;

    Florida Int Univ Dept Hlth Promot & Dis Prevent Robert Stempel Coll Publ Hlth & Social Work Miami FL 33199 USA|Baptist Hlth South Florida Ctr Adv Analyt Coral Gables FL USA;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Viral suppression; PLHIV; Trinidad and Tobago; MSM; individual factors;

    机译:病毒抑制;艾滋病毒特立尼达和多巴哥;MSM;个人因素;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号