We want remission, but what is it?

摘要

The treatment of rheumatoid arthritis hasnundergone marked changes in the last 50 years.nOrganic gold therapy, first tested in a controlledntrial in the 1960s, was a major step towardsneffective treatment of rheumatoid arthritis [1].nMethotrexate therapy and NSAIDs increasednthe armamentarium of useful drugs for thentreatment of this condition [2,3]. More recently,nbiologic therapy has resulted in another majornstep forward (see below).nIn the late 1980s and 1990s, two closelynrelated events further advanced the therapy ofnrheumatoid arthritis: