Determination of In Vitro Lung Solubility and Intake-to-Dose Conversion Factors for Tritiated LaNi_(4.15)Al_(0.85) and 13X Zeolite

摘要

Samples of tritiated LaNi4.15Al0.85 (LANA. 85) and 13X zeolite were analyzed to obtain particle size distributions and tritium evolution rates in a simulated lung environment. This information was used to calculate intake-to-dose conversion factors (DCFs), which estimate the committed effective dose (CED) a worker would receive after inhaling either tritiated particulate. The DCFs for tritiated LANA. 85 and 13X particulate with a default activity mean aerodynamic diameter (AMAD) of 5 mu m were determined to be 1.01E-11 Sv/Bq and 1.11E-11 Sv/Bq, respectively. These results are comparable to that of HTO, 1.8E-11 Sv/Bq, indicating that urine bioassay results can conservatively estimate the dose delivered if the worker was exposed to any mixture of HTO, LANA. 85, or 13X.