PARASITOLOGY

摘要

Natural resistance-associated macrophage proteins (Nramp) are multispecific symporters facilitating proton-dependent import of divalent metals. Nrampl restricts microbial access to essential micro-nutrients such as iron and manganese within professional phagosomes. Increased understanding of Nrampl roles in human phagocytes will be useful for future therapeutic approaches against selected infectious and immune diseases.