Association of primary tumour FDG uptake with clinical, histopathological and molecular characteristics in breast cancer patients scheduled for neoadjuvant chemotherapy

B. B. Koolen; M. J. T. F. D. Vrancken Peeters; J. Wesseling; E. H. Lips; W. V. Vogel; T. S. Aukema; E. van Werkhoven; K. G. A. Gilhuijs; S. Rodenhuis; E. J. Th. Rutgers; R. A. Valdés Olmos

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Association of primary tumour FDG uptake with clinical, histopathological and molecular characteristics in breast cancer patients scheduled for neoadjuvant chemotherapy

机译：计划进行新辅助化疗的乳腺癌患者原发性肿瘤FDG摄取与临床，组织病理学和分子特征的关系

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摘要

The aim of this study was to evaluate the association of primary tumour 18F-fluorodeoxyglucose (FDG) uptake with clinical, histopathological and molecular characteristics of breast cancer patients scheduled for neoadjuvant chemotherapy. Second, we wished to establish for which patients pretreatment positron emission tomography (PET)/CT could safely be omitted because of low FDG uptake.

机译：本研究的目的是评估原发性肿瘤18 F-氟脱氧葡萄糖（FDG）摄取与计划进行新辅助化疗的乳腺癌患者的临床，组织病理学和分子特征之间的关系。其次，我们希望确定哪些患者因FDG摄取量低而可以安全地省略正电子发射断层扫描（PET）/ CT的患者。

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来源
《European Journal of Nuclear Medicine and Molecular Imaging 》 |2012年第12期| p.1830-1838| 共9页
作者
B. B. Koolen; M. J. T. F. D. Vrancken Peeters; J. Wesseling; E. H. Lips; W. V. Vogel; T. S. Aukema; E. van Werkhoven; K. G. A. Gilhuijs; S. Rodenhuis; E. J. Th. Rutgers; R. A. Valdés Olmos;
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作者单位

Department of Nuclear Medicine, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands;

Department of Surgical Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands;

Department of Pathology and Experimental Therapy, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands;

Department of Pathology and Experimental Therapy, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands;

Department of Nuclear Medicine, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands;

Department of Nuclear Medicine, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX, Amst;

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正文语种 eng
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关键词
Breast cancer; PET/CT; Subtype; Prognosis; Characteristics; Response monitoring;

机译：乳腺癌;PET / CT;亚型;预后;特征;反应监测;

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专利

1. Association of primary tumour FDG uptake with clinical, histopathological and molecular characteristics in breast cancer patients scheduled for neoadjuvant chemotherapy. [J] . B B Koolen, M J T F D Vrancken Peeters, J Wesseling, European Journal of Nuclear Medicine and Molecular Imaging . 2012 ,第12期

机译：计划进行新辅助化疗的乳腺癌患者的原发性肿瘤FDG摄入量与临床，组织病理学和分子特征有关。
2. Locally advanced/inflammatory breast cancers treated with intensive epirubicin-based neoadjuvant chemotherapy: are there molecular markers in the primary tumour that predict for 5-year clinical outcome? [J] . Bonnefoi H, Diebold Berger S, Therasse P, Annals of oncology: official journal of the European Society for Medical Oncology . 2003 ,第3期

机译：基于表柔比星强化新辅助化疗治疗的局部晚期/炎症性乳腺癌：原发性肿瘤中是否存在分子标志物可预测5年临床结果？
3. (18)FDG-PET/CT Imaging in Breast Cancer Patients with Clinical Stage IIB or Higher Commentary on "Overuse of Preoperative Staging of Patients Undergoing Neoadjuvant Chemotherapy for Breast Cancer" by Marissa K. Srour et al. [J] . Annals of surgical oncology . 2020 ,第5期

机译：（18）乳腺癌患者的FDG-PET / CT成像患者临床阶段IIB或更高的评论“过度评论”过度使用营养术前分期对乳腺癌进行乳腺癌进行乳腺癌的术前分期“，Marissa K.Srour等人。
4. Preliminary Experiences of DBT (digital breast tomosynthesis) and Hybrid 18F-FDG-PET/MR (PETMR) for Neoadjuvant Chemotherapy (NAC) Cases in Breast Cancer [C] . Nachiko Uchiyama MD, Hiroaki Kurihara MD, Takayuki Kinoshita MD, International Workshop on Breast Imaging . 2018

机译：DBT（数字乳腺断层合成）和混合18F-FDG-PET / MR（PETMR）在乳腺癌新辅助化疗（NAC）病例中的初步经验
5. Coregistration of serial breast MR studies for augmenting neoadjuvant chemotherapy response evaluation in breast cancer patients. [D] . Chittineni, Ruparani. 2008

机译：增强乳腺癌患者新系列辅助化疗反应评估的系列乳房MR研究的核心。
6. Metabolic Radiomics for Pretreatment 18F-FDG PET/CT to Characterize Locally Advanced Breast Cancer: Histopathologic Characteristics Response to Neoadjuvant Chemotherapy and Prognosis [O] . Seunggyun Ha, Sohyun Park, Ji-In Bang, -1

机译：代谢放射学用于18F-FDG PET / CT预处理以表征局部晚期乳腺癌：组织病理学特征对新辅助化疗的反应和预后
7. Correlation of Primary Tumor Metabolic Parameters with Clinical, Histopathological and Molecular Characteristics in Breast Cancer Patients at Preoperative Staging FDG-PET/CT Study [O] . AA Mohamed, AM Zaher, MI Khalifa, 2021

机译：主要肿瘤代谢参数与胸腺癌患者临床，组织病理学和分子特征在术前分期术前分期术术术术前分期性FDG-PET / CT研究

Association of primary tumour FDG uptake with clinical, histopathological and molecular characteristics in breast cancer patients scheduled for neoadjuvant chemotherapy

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