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The short-term effect of 24-h average and peak air pollution on mortality in Oslo, Norway

机译:挪威奥斯陆24小时平均和峰值空气污染对死亡率的短期影响

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Numerous epidemiological studies have shown associations between increases in outdoor air pollution and all-cause mortality as well as cardiovascular and respiratory related mortality. The majority of studies has used the routine monitoring network and thus has not been able to characterize the small-scale variation in daily averages and peak concentrations within urban settings. To address possible short term impact on mortally by air pollution we used a time-stratified case-crossover design to estimate associations of traffic-related air pollution and wood burning and daily mortality during a period of 10 years among residents above 50 years of age in Oslo, Norway. A dispersion model was used to assess short-term air pollution for daily (24-h) averages and peak concentrations of nitrogen dioxide (NO2) from exhaust and particulate matter with a diameter of 2.5 μm or less (PM2.5) from exhaust and wood-burning at residential neighbourhood level for each individual. We found an overall increased risk from exposure at the lag of 0–5 days before the day of death for both pollutants. The excess risk was highest for PM2.5 with a 2.8 % (95 % confidence interval: 1.2–4.4) increase per 10 μg per cubic meter change in daily exposure. Short-term traffic-related air pollution was associated with increased risk for mortality among individuals above 50 years of age, especially for circulatory outcomes.
机译:大量的流行病学研究表明,室外空气污染的增加与全因死亡率以及与心血管和呼吸有关的死亡率之间存在关联。大多数研究都使用了常规监测网络,因此无法描述城市环境中日均浓度和峰值浓度的小范围变化。为了解决空气污染可能对人类造成的短期影响,我们使用了时间分层的案例交叉设计来估算与交通相关的空气污染与木材燃烧以及10岁以上50岁以上居民在10年内的每日死亡率之间的关系。挪威奥斯陆。使用扩散模型评估每日平均(24小时)的短期空气污染以及直径和等于或小于2.5μm(PM2.5)的颗粒物排放的二氧化氮(NO2 )的峰值浓度)在每个居民区的排烟和燃木。我们发现两种污染物在死亡之日前0-5天的延迟中,暴露的风险总体增加。 PM2.5 的额外风险最高,每天每立方米变化10μg,则增加2.8%(95%置信区间:1.2–4.4)。与交通有关的短期空气污染与50岁以上的人死亡风险增加相关,尤其是循环系统结果。

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