Strong association between HLA-B*1502 and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in mainland Han Chinese patients

Yan Zhang; Jin Wang; Li-Mei Zhao; Wei Peng; Guo-Qing Shen; Ling Xue; Xiao-Xian Zheng; Xiao-Jing HE; Chun-Yan Gong; Li-Yan Miao

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Strong association between HLA-B*1502 and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in mainland Han Chinese patients

机译：HLA-B * 1502与卡马西平诱导的史蒂文斯-约翰逊综合征与中国大陆汉族患者的毒性表皮坏死溶解之间密切相关

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摘要

The purpose of this study is to examine the association of HLA-B*1502 allele with CBZ-induced SJS/TEN in the mainland Han Chinese population.

机译：这项研究的目的是检查中国大陆汉族人群中HLA-B * 1502等位基因与CBZ诱导的SJS / TEN的关联。

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来源
《European Journal of Clinical Pharmacology》 |2011年第9期|p.885-887|共3页
作者
Yan Zhang; Jin Wang; Li-Mei Zhao; Wei Peng; Guo-Qing Shen; Ling Xue; Xiao-Xian Zheng; Xiao-Jing HE; Chun-Yan Gong; Li-Yan Miao;
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作者单位

Department of Clinical Pharmacology Research Lab, The First Affiliated Hospital of Soochow University, Suzhou, China;

Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Soochow University School of Pharmacy, Suzhou, China;

Department of Pharmacy, Shengjing Hospital of China Medical University, Shenyang, China;

Department of Clinical Pharmacology Research Lab, The First Affiliated Hospital of Soochow University, Suzhou, China;

Hospital of Dermatology, Chinese Academy of Medical Sciences, Nanjing, China;

Department of Clinical Pharmacology Research Lab, The First Affiliated Hospital of Soochow University, Suzhou, China;

Department of Clinical Pharmacology Research Lab, The First Affiliated Hospital of Soochow University, Suzhou, China;

Department of Pharmacy, Shengjing Hospital of China Medical University, Shenyang, China;

Hospital of Dermatology, Chinese Academy of Medic;

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正文语种 eng
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关键词
HLA-B*1502; Carbamazepine; Stevens-Johnson syndrome; Toxic epidermal necrolysis; Mainland Chinese;

机译：HLA-B * 1502;卡马西平;Stevens-Johnson综合征;中毒性表皮坏死;中国内地;

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专利

1. Strong association between HLA-B*1502 and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in mainland Han Chinese patients. [J] . Zhang Y, Wang J, Zhao LM, European journal of clinical pharmacology . 2011,第9期

机译：HLA-B * 1502与卡马西平诱发的史蒂文斯-约翰逊综合症与中国大陆汉族患者的毒性表皮坏死溶解之间密切相关。
2. Association of HLA-B*1502 allele with lamotrigine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese subjects: a meta-analysis [J] . Zeng Tao, Long Yue-Sheng, Min Fu-Li, International journal of dermatology . 2015,第4期

机译：HLA-B * 1502等位基因与拉莫三嗪诱导的史蒂文斯-约翰逊综合征和中毒性汉族表皮坏死的关联：一项荟萃分析
3. Association of HLA-B*1502 allele with lamotrigine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese subjects: a meta-analysis [J] . Zeng Tao, Long Yue-Sheng, Min Fu-Li, International journal of dermatology . 2015,第4期

机译：HLA-B * 1502等位基因与汉语诱导的史蒂文氏症 - 约翰逊综合征和汉族人群有毒表皮死亡症：META分析
4. Association of HLA-B*5101 and Characteristics of Patients with Behcet's Disease in China using HLA-B51 OligoChip [C] . Sun Yuping, Shen Hong, Liu Jie, International Forum on Progress on Post-Genome Technologies(5'IFPT); 20070910-11; Suzhou(CN) . 2007

机译：HLA-B51 OligoChip与HLA-B * 5101和中国白塞氏病患者特征的关联
5. Association of the HLA-B alleles with carbamazepine-induced Stevens–Johnson syndrome/toxic epidermal necrolysis in the Javanese and Sundanese population of Indonesia: the important role of the HLA-B75 serotype [O] . Rika Yuliwulandari, Erna Kristin, Kinasih Prayuni, -1

机译：HLA-B等位基因与卡马西平诱发的史蒂文斯-约翰逊综合症/毒性表皮坏死溶解在印度尼西亚的爪哇和Sun那德人群中的关联：HLA-B75血清型的重要作用
6. Relationship between the HLA-B*1502 allele and carbamazepine-induced Stevens-Johnson Syndrome and toxic epidermal necrolysis: a systematic review and meta-analysis [O] . Tangamornsuksan Wimonchat, Chaiyakunapruk Nathorn, Somkrua Ratchadaporn, 2013

机译：HLA-B * 1502等位基因与卡马西平诱导的史蒂文斯-约翰逊综合症与毒性表皮坏死溶解之间的关系：系统评价和荟萃分析

Strong association between HLA-B*1502 and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in mainland Han Chinese patients

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