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The use of metallic expandable tracheal stents in the management of inoperable malignant tracheal obstruction

机译:金属可扩张气管支架在无法手术的恶性气管阻塞治疗中的应用

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Tracheal neoplasms account for less than 1% of all malignancies. In spite of their low incidence, these tumors represent potentially lethal phenomena. In cases of airway compromise and unresectable disease, the airway may be maintained by repeated bronchoscopic debulkings, and the use of CO2 laser, silicone Montgomery T-tube and tracheal stents. The use of metallic expandable stents to relieve airway obstruction in advanced tracheal tumors was previously reported. Our aim was to evaluate the use of metallic expandable tracheal stents as a palliative relief from severe airway obstruction in cases of locally advanced, inoperable malignant tracheal tumors. Patients suffering from severe airway obstruction secondary to locally advanced tracheal tumors, who presented to the Otolaryngology Head and Neck Surgery and Chest Diseases Departments at the Main Alexandria University Hospital, Egypt, were included in this study. After endoscopic and radiological evaluation, expandable metallic tracheal stents (SENS; Ultraflex tracheal prosthesis; Boston Scientific Corp, Watertown, MA, USA) were inserted under general anesthesia to relieve airway obstruction. Postoperative follow-up with regard to improvement of respiration, tolerability of the stent and reporting of complications was done. Twelve patients were included, eight males and four females with a mean age of 61 years. Four patients (33.3%) had primary tracheal tumors and eight (66.7%) suffered from tumors infiltrating the trachea from nearby structures. The stent was easily inserted in all patients with no significant intraoperative complications. Postoperatively, the stent was well tolerated and all patients experienced good respiration with significant improvement of respiratory function test results. The most common complication reported was granulation tissue formation. Other complications were displacement of the stent, bad breath, re-growth of tumor tissue at the lower end of the stent and retention of secretions. We concluded that Ultraflex self-expandable stent is a good alternative for palliative relief from airway obstruction in cases of inoperable malignant tracheal tumors. Strict follow-up is mandatory for early detection and management of expected complications.
机译:气管肿瘤占所有恶性肿瘤的不到1%。尽管它们的发病率较低,但它们仍代表着潜在的致命现象。如果发生气道受损和无法切除的疾病,可通过反复的支气管镜检查术以及使用CO 2 激光,硅胶Montgomery T型管和气管支架来维持气道。先前已经报道了使用金属可扩展支架来减轻晚期气管肿瘤中的气道阻塞。我们的目标是评估在局部晚期无法手术的恶性气管肿瘤的情况下,使用金属可扩张气管支架作为缓解严重气道阻塞的姑息缓解方法。该研究包括埃及本地亚历山大大学医院耳鼻咽喉头颈外科和胸部疾病科的继发于局部晚期气管肿瘤的严重气道阻塞患者。经过内窥镜和放射学评估后,在全身麻醉下插入可扩张的金属气管支架(SENS; Ultraflex气管假体;波士顿科学公司,美国马萨诸塞州沃特敦),以缓解气道阻塞。进行了有关呼吸改善,支架耐受性和并发症报告的术后随访。包括十二名患者,八名男性和四名女性,平均年龄为61岁。四名患者(33.3%)患有原发性气管肿瘤,八名患者(66.7%)患有从附近结构渗入气管的肿瘤。所有患者均易于插入支架,术中无明显并发症。术后支架耐受性良好,所有患者呼吸良好,呼吸功能测试结果显着改善。报告的最常见并发症是肉芽组织形成。其他并发症包括支架移位,口臭,支架下端肿瘤组织的重新生长以及分泌物的保留。我们得出的结论是,在无法手术的恶性气管肿瘤的情况下,Ultraflex自膨式支架是缓解姑息性气道阻塞的良好选择。为了尽早发现和处理预期的并发症,必须进行严格的随访。

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