Susceptibility of early life stages of xenopus laevis to cadmium

摘要

The susceptibility of Xenopus laevis to cadmium during different stages of development was evaluated by exposing embryos to cadmium concentrations ranging from 0.1 to 10 mg Cd~2+/L for 24, 48, and 72 h and assessing lethality and malformations. Susceptibility increased from the two blastomeres stage (stage 2) to stage 40, in which the 24-h LC100 was 1.13 mg Cd~2+/L, and Resistence increased from this stage onward. Malformations occurred at all developmental stages evaluated, the most common being Reduced size, incurvated axis, underdeveloped or abnormally developed fin, microcephaly, and microphtalmy.