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A comparison of the toxicity and metabolism of phenol and chlorinated phenols by lemna gibba, with special reference to 2, 4, 5-trichlorophenol

机译:lemna gibba对苯酚和氯化苯酚的毒性和代谢的比较,特别涉及2,4,5,三氯苯酚

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摘要

The toxicity of a series of chlorinated phenols, from phenol to pentachlorophenol, was determined using frond repro- duction in aseptically grown Lemna gibba. The toxicities of the phenols tended to increase as the number of chlorine substituents on the phenol ring increased. The plants metabolized each of the phenols in the same manner producing metabolites that were more polar than their parent compounds. The metabolite for 2, 4, 5-trichlorophenol was isolated and identified by nuclear magnetic resonance spectroscopy and chemical ionization mass spectroscopy.
机译:在无菌生长的Lemna gibba中使用叶状复制测定了从苯酚到五氯苯酚的一系列氯化苯酚的毒性。随着苯酚环上氯取代基数目的增加,苯酚的毒性趋于增加。植物以相同的方式代谢每种酚,从而产生比其母体化合物极性更大的代谢产物。通过核磁共振波谱法和化学电离质谱法分离并鉴定了2、4、5-三氯苯酚的代谢物。

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