The Environmental Degradation and Distribution of Saflufenacil, a Fluorinated Protoporphyrinogen Ⅸ Oxidase–Inhibiting Herbicide, on a CanadianWinter Wheat Field

摘要

Saflufenacil when applied to a field is susceptible to transport, degradation, and transformation. We used a laboratory-based approach to model the fate of saflufenacil in the environment, the results of which are compared directly with those observed in a field study where saflufenacil was applied to a crop of winter wheat at a standard rate of 63 g of active ingredient/hectare. The water solubility of 2.1 g/L for saflufenacil allows for vertical transport through soil at a rate of 4.3 cm/mL of rainwater, and a soil adsorption coefficientK(OC)of 28.8 suggests that some of the herbicide will absorb to the soil. Of the saflufenacil in the soil, 78 +/- 2.1% (n = 18) partitioned into plants, including nontargeted crop species, where it was found primarily in leaves (78 +/- 2.1%,n = 18) and roots (22 +/- 1.7%,n = 18). The saflufenacil that does not partition into plants or undergo vertical transport followed a degradation pathway into 3 metabolites: a uracil-ring N-demethylated metabolite (Saf-mu CH3), a doubly N-demethylated metabolite (Saf-2CH(3)), and a ring-cleavage metabolite (Saf-RC), identified using nontargeted mass spectrometry. In the field, saflufenacil was observed to degrade over 212 d to the persistent metabolite Saf-RC. This metabolite was found at a concentration that was 1/10th of that applied to the field, suggesting that the majority of saflufenacil had undergone transport through the soil, or uptake into the winter wheat crop. Field samples were further examined using F-19 nuclear magnetic resonance and nontargeted mass spectrometry to rule out the potential of other degradation products.Environ Toxicol Chem2020;00:1-11. (c) 2020 SETAC