Toxicity and Mechanisms of Action of Polycyclic Aromatic　Hydrocarbon Pollution in Red Algae (Gracilaria corticata) from　the Northern Coast of the Oman Sea

摘要

The activities of selected biomarkers including 7-ethoxycoumarin-O-deethylase (ECOD) and glutathione S-transferase (GST) were measured in the red algae (Gracilaria corticata) obtained from the Oman Sea. Chemical analyses were used to assess the polycyclic aromatic hydrocarbons (PAHs) in the red algae. Total PAH concentrations in the red algae ranged from 3.61 to 8.14 ng g(-1) dry weight. Mean GST and ECOD activity also varied from 8.87 to 15.32 nmol/mg protein/min and from 0.31 to 1.02 pmol/min/mg protein, respectively. Significant correlations were found between the total PAH levels and the selected biomarkers (p 0.01). The results showed that ECOD and GST enzymes reacted to PAHs in phase I and II detoxification mechanisms of red algae (G. corticata), which extend the use of these biomarkers for investigation of the biological effects of PAH pollution as well as determination of pollution bioavailability. Environ Toxicol Chem 2019;38:1947-1953. (c) 2019 SETAC.