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Occurrence and Potential Significance of Perfluorooctanoic Acid (PFOA) Detected in New Jersey Public Drinking Water Systems

机译:新泽西州公共饮用水系统中检测到的全氟辛酸(PFOA)的发生及其潜在意义

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摘要

After detection of perfluorooctanoic acid (PFOA) in two New Jersey (NJ) public water systems (PWS) at concentrations up to 0.19 μg/L, a study of PFOA in 23 other NJ PWS was conducted in 2006. PFOA was detected in 15 (65%) of the systems at concentrations ranging from 0.005 to 0.039 μg/L To assess the significance of these data, the contribution of drinking water to human exposure to PFOA was evaluated, and a health-based drinking water concentration protective for lifetime exposure of 0.04 μg/L was developed through a risk assessment approach. Both the exposure assessment and the health-based drinking water concentrations are based on the previously reported 100:1 ratio between the concentration of PFOA in serum and drinking water in a community with highly contaminated drinking water. The applicability of this ratio to lower drinking water concentrations was confirmed using data on serum levels and water concentrations from other communities. The health-based concentration is based on toxicological end points identified by U.S. Environmental Protection Agency (USEPA) in its 2005 draft risk assessment. Recent information on PFOA'stoxicity not considered in the USEPA risk assessment further supports the health-based concentration of 0.04 μg/L In additional sampling of 18 PWS in 2007-2008, PFOA in most systems was below the health-based concentration. However, PFOA was detected above the health-based concentration in five systems, including one not previously sampled.
机译:在两个新泽西州(NJ)公共供水系统(PWS)中检测到全氟辛酸(PFOA)浓度高达0.19μg/ L之后,2006年对另外23个新泽西州PWS中的PFOA进行了研究。在15个州中检测到PFOA( 65%的系统浓度在0.005至0.039μg/ L范围内为了评估这些数据的重要性,评估了饮用水对人体暴露于PFOA的贡献,并基于健康的饮用水浓度对终生暴露有保护作用。通过风险评估方法开发出0.04μg/ L。暴露评估和基于健康的饮用水浓度均基于先前报告的高度污染饮用水社区中血清和饮用水中PFOA的浓度之比100:1。使用血清水平和其他社区的水浓度数据证实了该比率对降低饮用水浓度的适用性。基于健康的浓度基于美国环境保护署(USEPA)在其2005年风险评估草案中确定的毒理学终点。 USEPA风险评估中未考虑的有关PFOA毒性的最新信息进一步支持了基于健康的0.04μg/ L浓度。在2007-2008年对18个PWS的额外采样中,大多数系统中的PFOA均低于基于健康的浓度。但是,在五个系统中检测到的PFOA高于健康浓度,包括一个以前未采样的系统。

著录项

  • 来源
    《Environmental Science & Technology》 |2009年第12期|4547-4554|共8页
  • 作者单位

    Division of Science, Research and Technology, New Jersey Department of Environmental Protection, P.O. Box 409, Trenton, New Jersey 08625;

    Division of Science, Research and Technology, New Jersey Department of Environmental Protection, P.O. Box 409, Trenton, New Jersey 08625;

    Department of Biochemistry and Microbiology, Rutgers University, 76 Lipman Drive, Room 218, New Brunswick, New Jersey 08901;

    Bureau of Safe Drinking Water, New Jersey Department of Environmental Protection, P.O. Box 426, Trenton, New Jersey 08625;

    Division of Science, Research and Technology, New Jersey Department of Environmental Protection, P.O. Box 409, Trenton, New Jersey 08625;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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  • 入库时间 2022-08-17 14:04:48

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