Comment on 'Application of the Activity Framework for Assessing Aquatic Ecotoxicology Data for Organic Chemicals'

摘要

We offer the following comments to the paper of Thomas et al. The authors apply the activity concept to experimental data of nonspecific toxicity. The goal is to identify a systematic relationship that would then help to predict toxic effects for untested chemicals. However, it appears to us that the suggested approach is a step backward in our process understanding and chemical risk management rather than a step forward.