Per- and Polyfluoroalkyl Substances (PFASs) in Indoor Air and Dust from Homes and Various Microenvironments in China: Implications for Human Exposure

摘要

A newly developed solid-phase extraction cartridge composed of mixed sorbents was optimized for collection of both neutral and ionizable per- and polyfluoroalkyl substances (PFASs) in indoor air. Eighty-one indoor air samples and 29 indoor dust samples were collected from rooms of homes and hotels, textile shops, and cinemas in Tianjin, China. Fluorotelomer alcohols (FTOHs) were the predominant PFASs found in air (250–82 300 pg/m~(3)) and hotel dust (24.8–678 ng/g). Polyfluoroalkyl phosphoric acid diesters were found at lower levels of nd–125 pg/m~(3) in air and 0.32–183 ng/g in dust. Perfluoroalkyl carboxylic acids (PFCAs) were dominant ionizable PFASs in air samples (121–20 600 pg/m~(3)) with C4–C7 PFCAs contributing to 54% ± 17% of the profiles, suggesting an ongoing shift to short-chain PFASs. Long-chain PFCAs (C > 7) were strongly correlated and the intermediate metabolite of FTOHs, fluorotelomer unsaturated carboxylic acids, occurred in all the air samples at concentrations up to 413 pg/m~(3), suggesting the transformation of precursors such as FTOHs in indoor environment. Daily intake of ∑PFASs via air inhalation and dust ingestion was estimated at 1.04–14.1 ng/kg bw/d and 0.10–8.17 ng/kg bw/d, respectively, demonstrating that inhalation of air with fine suspended particles was a more important direct exposure pathway than dust ingestion for PFASs to adults.