Acute Gastrointestinal Effects of Graded Levels of copper in Drinking Water

摘要

The objective of this study was to determine the acute gastrointestinal effects caused by the con- sumption of drinking water containing graded levels of added copper. Sixty healthy, adult women were randomly assigned to receive copper [Cu(II)] at four concentrations in their drinking water following a Latin-square design. Each group (n= 15) received tap water with no added copper, 1, 3, and 5 mg Cu/l of added copper sulfate for a 2-week study period, followed by 1 week of stan- dard tap water.