Cholinergic and Behavioral Neurotoxicity of Carbaryl and Cadmium to Larval Rainbow Trout(Oncorhynchus makiss)

摘要

Pesticides and heavy metals are common environmental con- taminants that can cause neurotoxicity to aquatic organisms, impairing reproduction and survival. Neurotoxic effects of cab- mium and carbaryl exposure were estimated in larval rainbow trout(RBT; Oncorhynchus mykiss)using changes in physiolo- gical endpoints and correlations with behavioral responses. Fol- lowing exposures, RBT were videotaped to assess swimming speed. Brain tissue was used to measure cholinesterase(ChE) activity, muscarinic cholinergic receptor(MChR)number, and MChR affinity.