Relationship between glycated haemoglobin levels and mean glucose levels over time

摘要

HbA1c, expressed as the percentage of adult haemoglobin that is glycated, is the most widely used measure of chronic glycaemia. Achieving near-normal HbA1c levels has been shown to reduce long-term complications and the HbA1c assay is recommended to determine whether treatment is adequate and to guide adjustments. However, daily adjustments of therapy are guided by capillary glucose levels (mmol/l). We determined the relationship between an accurate measure of mean glucose levels over time and the HbA1c level, and whether HbA1c can be expressed in the same units as self-monitoring results.