Nonalcoholic fatty liver disease: a feature of the metabolic syndrome

摘要

Insulin sensitivity(euglycemic clamp, insulin infusion rate: 40 mU.m~-2.min~-1)was studied in 30 subjects with biopsy-proven nonalcoholic fatty liver disease(NAFLD), normal glucose tolerance, and a BMI < 30 kg/m~2. Of those 30 subjects, 9 had pure fatty liver and 21 had evidence of steatohepatitis. In addition, 10 patients with type 2 diabetes under good metabolic control and 10 healthy subjects were studied.