Does Obesity-Induced τ Phosphorylation Tip the Scale Toward Dementia?

摘要

Obesity, a worldwide epidemic with numerous health implications, is gaining traction as a risk factor for dementia. The need for research is evident: at least 2.8 million obese or overweight adults die each year according to the World Health Organization, and more than two-thirds of American adults are overweight or obese. Obesity increases the risk of several health conditions, including hypertension, dyslipi-demia, insulin resistance, and type 2 diabetes. In addition, obesity, as well as type 2 diabetes, increases the risk of cognitive dysfunction and dementia.