Neurological complications of COVID-19: Another battle

摘要

COVID-19 is one of the most severe crises of the last decades, with unprecedented and unpredictable losses. COVID-19 is mainly a disease with respiratory symptoms, but cardiovascular and neurological complications are more and more reported and should not be ignored. Some patients with COVID-19 experience delirium during hospitalization, with confusion, agitation and disorientation. The neurological complications are insufficiently known and they may alter the prognosis of these patients. The researchers struggle to understand why these neurological signs appear, who is at higher risk and how they should be managed. Two hypotheses have been advanced: the first one is related to the direct viral invasion and infection of the brain and the second one to an overstimulation of the immune system. The appropriate treatment of the neurological signs depends on the correct knowledge and understanding of the pathophysiological mechanisms.