Isolation and Characterization of Multiple Drug Resistant Human Enteric Pathogens from Sewage Water of Delhi

摘要

Antibiotic resistance is one of the major problems in the medical world, and the sewage waters are the primary habitats to harbour antibiotic resistance bacteria (ARB) especially multi-drug resistance (MDR) human enteric pathogens. The present study dealt with isolation, identification and characterization of human enteric pathogens showing resistance against ten different commonly prescribed antibiotics. These bacterial strains were isolated from different sewage treatment plants located in the suburb of Delhi. Initially, samples were analysed for the presence of pathogenic human enteric bacteria through morphological, biochemical and molecular analysis. Further susceptibility patterns of these isolates were studied towards clinically significant antibiotics. Doxycycline and Metronidazole were found to be most inert antibiotic as it was ineffective against all isolated enteric pathogens, whereas Meropenem was found to be most promising antibiotic. As the resistance of these microorganisms is evolving day by day, proper steps should be taken to prevent it.