GC-MS METABOLITE PROFILING OF BIOACTIVE COMPOUNDS IN LEAF, FRUIT AND SEED EXTRACTS OF SYZYZIUM CUMINI (L.)

摘要

The present study aimed to explore the primary metabolites present in leaf, fruit, and seed crude extracts of Syzygium cumini L by Gas chromatography – Mass spectrometry. The compounds in the leaf, seed, and fruit extracts resulted from the GC-MS analysis was relevant to the National Institute of Standards and Technology (NIST) library. The metabolite profiling of the extracts revealed the presence of carboxylic acid and fatty acid found to be common in leaf, fruit, and seed extracts. And metabolites 6-oxa-3-thiaoctanoic acid, bisoprolol, phenacetin, tropin, alizarin, gonodoic acid are present in seeds that are not found in leaves and fruit metabolite profile. In contrast, Tetra decanoic acid, Azelaic acid, Penicillamine and S (-)-Cathinone are found only in leaves. Leaf, fruit and seed extracts of Syzyzium cumini L contains various bioactive compounds and consequently has a variety of medicinal properties for the treatment of different diseases like thyroid cancer, heart diseases, kidney stones and rheumatoid arthritis. Some metabolites found to be active as antidiabetic, anti-inflammatory, anti-cancerous, antioxidant, anti-bacterial and antifungal activities identified in leaf, fruit and seed extracts of Syzyzium cumini L. This study may pave the way for the production of herbal medicines for various ailments using leaf, fruit, and seed extracts of Syzyzium cumini L.