首页> 外文期刊>Annals of Dermatology >Combination Treatment of Intra/Perilesional Botulinum Toxin-A Injection and Ablative Fractional Laser for Better Clinical Outcomes of Hypertrophic Fibrotic Thyroidectomy Scars Following Fractional Ablative Laser Resurfacing
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Combination Treatment of Intra/Perilesional Botulinum Toxin-A Injection and Ablative Fractional Laser for Better Clinical Outcomes of Hypertrophic Fibrotic Thyroidectomy Scars Following Fractional Ablative Laser Resurfacing

机译:胞内/悬雍外肉毒杆菌的组合治疗 - 一种注射和烧蚀分数激光器,用于更好地临床结果的分数烧蚀激光重新铺设后的肥厚纤维型甲状腺切除术瘢痕

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Background: Recent reports have shown that intralesional botulinum toxin type-A (BTX-A) works on scar cosmesis. Objective: To evaluate the clinical efficacy of combination treatment of laser and BTX-A injection and compare the effects of conventional intralesional injection and intra- and perilesional BTX-A injection on fibrotic thyroidectomy scars. Methods: Patients with fibrotic thyroidectomy scars showing insufficient responses to previous ablative fractional laser (AFL) treatment were enrolled. Combination treatment with AFL and BTX-A injection was performed. Patients who received intra/perilesional BTX-A injections were classified into group A. Group B was patients in whom the injection was performed only intralesionally. The improvement was assessed based on the Vancouver Scar Scale (VSS). Results: A total of 24 patients was included. Statistically significant improvement in pliability and total VSS score after the combination treatment were observed in overall patient group. Subgroup analysis demonstrated that pliability, height, and total VSS improved significantly in group A. In group B, only pliability significantly improved. Conclusion: BTX-A injection combined with AFL can provide better relief for the previously treated fibrotic thyroidectomy scars. Injection of BTX-A not only into the scar itself, but also into perilesional muscles that can exert tension on the scar site may provide additional benefit in flattening scar height.
机译:背景:最近的报道表明,内部肉毒杆菌毒素类型-A(BTX-A)适用于瘢痕杂物。目的:评价激光和BTX的联合治疗的临床疗效,并比较常规腔内注射和血液中的血管异常BTX-A注射对纤维化甲状腺切除术瘢痕的影响。方法:纤维化甲状腺切除术瘢痕的患者显示出对先前烧蚀的分数激光(AFL)处理的反应不充分的伤害。用AFL和BTX-A注射进行组合处理。接受内部/悬雍外的BTX-A注射的患者分为A组。B组是注射患者仅在内的患者。基于温哥华疤痕量表(VSS)评估了改进。结果:共有24名患者。在整个患者组中观察到组合治疗后,尺寸显着改善和总VSS评分。亚组分析表明,A型抗性,高度和总VSS在A组中显着改善。在B组中,只有宽度地改善了宽度。结论:BTX-A注射与AFL结合,可以为先前治疗的纤维化甲状腺切除术疤痕提供更好的缓解。注射BTX-A不仅进入疤痕本身,还进入了可以在疤痕网站上施加张力的悬雍垂肌肉可以在平坦疤痕高度方面提供额外的益处。

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