Saini, S. & R. A. Bhat, 2021. Immunohistological localisation of growth factors in stroma and interstitial gland tissue of goat (Capra hircus) ovary. Bulg. J. Vet. Med., 24, No 4, 478-486

摘要

The growth factors platelet derived growth factor (PDGF), transforming growth factor alpha (TGF-伪) and transforming growth factor beta (TGF-尾) have been demonstrated to stimulate the聽in vitro聽prolife颅ration of theca and granulosa cells in different animals. The present study was conducted to localise the growth factors PDGF, TGF-伪 and TGF-尾 in different types of interstitial cells and stromal cells of normal cycling goat ovaries. Tissue fixed in formalin was processed through a graded series of alcohols and embedded in paraffin wax. The sections were immunohistochemically stained with antibo颅dies against PDGF, TGF-伪 and TGF-尾. The binding affinity of interstitial cells and stromal cells were observed and photographed. The staining pattern of PDGF, TGF-伪 and TGF-尾 was mild to strong in stromal cells. The primary and secondary interstitial cells exhibited varied staining patterns for all studied growth factors. These findings in goat suggests that PDGF, TGF-伪, TGF-尾 were potentially an important autocrine regulator of different cell functions and possibly a paracrine regulator of ovarian cell function at various development stages.