COVID-19 within a large UK prison with a high number of vulnerable adults, march to june 2020: An outbreak investigation and screening event

摘要

Objective To describe the public health response to COVID-19 within a large prison with a high number of clinically vulnerable residents. Design An outbreak investigation was undertaken among all residents and staff. A screening event involved nose and throat swab samples from residents and staff, examined by polymerase chain reaction (PCR). An electronic questionnaire regarding risk factors was distributed to staff. Results 58 residents out of 1,156 (5.0%, 95% CI: 3.8 – 6.3) and 129 staff out of 510 (25.3%, 95% CI: 21.5 – 29.1) displayed COVID-19 symptoms, including six and eight confirmed, respectively. Residents reported cough symptoms with no fever (29.3%), followed by a cough and fever (15.5%). 62.1% of symptomatic residents were 50 years or older, placing them in the group at risk for severe COVID-19 disease. Wing I had the highest attack rate (12.5%). 1,063 individuals were swabbed during the 5-day screening event, and all had negative swab results. Conclusion The findings were consistent with the hypothesis of a propagating outbreak with decreasing incidence since the peak date of onset. COVID-19 transmission within a high-risk setting was quickly contained, and an explosive outbreak was prevented through a multi-agency public health response.