Should we prescribe anticonvulsants for acute herpes zoster neuralgia and to prevent postherpetic neuralgia?: A protocol for meta-analysis and benefit-risk assessment

摘要

Herpeszoster,caused by reactivation ofthe dormant varicellazoster virus in asensory ganglia, is featured by unilateral distribution ofrash and pain. [1] Severezoster-associated pain, including both acute herpeszoster neuralgiaand postherpetic neuralgia, [2] has the potentialto significantly lower patient's quality oflifeand even limit daily activities.