High?drug resistance levels?could compromise?the control of HIV infection in paediatric and adolescent population in Kinshasa, the Democratic Republic of Congo

摘要

Background The inadequacy of HIV viraemia and resistance monitoring in Africa leads to uncontrolled circulation of HIV strains with drug resistance mutations (DRM), compromising antiretroviral therapy (ART) effectiveness. This study describes the DRM prevalence and its therapeutic impact in HIV-infected pediatric patients from Kinshasa (Democratic Republic of Congo, DRC).