• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>American Journal of Translational Research >The relationship between the carotid atherosclerosis ultrasound parameters and the cardiac and endothelial functions of coronary heart disease patients
【24h】

The relationship between the carotid atherosclerosis ultrasound parameters and the cardiac and endothelial functions of coronary heart disease patients

机译：冠心病患者颈动脉粥样硬化超声参数与心脏和内皮功能的关系

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose: This study aimed to discover the relationship between the carotid atherosclerosis ultrasound parameters and the cardiac and endothelial functions of coronary heart disease patients. Methods: 150 patients with coronary artery disease were divided into a single-branch group (one coronary artery with stenosis 50%), a double-branch group (two coronary arteries with stenosis 50%), and a multi-branch group (multiple coronary arteries with stenosis 50%) based on the severity of each patient’s coronary stenosis. Meanwhile, 50 healthy volunteers who were admitted to the hospital for routine health checks were recruited as the control group. This study tested the ultrasound parameters of carotid artery atherosclerosis among all the subjects in each group [common carotid artery sclerosis (β), carotid artery compliance (AC), elastic coefficient (Ep), pulse wave conduction velocity (PWVβ)], including the left ventricular end diastolic inner diameter (LVEDD), left ventricular ejection fraction (LVEF) and endothelial function parameters [endothelin-1 (ET-1), von Willebrand factor (vWF), and nitric oxide (NO)]. Results: The study found that the β, AC, Ep, PWVβ, LVEDD, LVESD, ET-1, and vWF levels of patients with coronary artery disease were all higher than the corresponding levels in the control group (P 0.05). The values increased as the number of coronary artery branches with stenosis increased (P 0.05). The LVEF and NO of the patients with coronary artery disease were lower than they were in the control group (P 0.05). The LVEF and NO decreased as the coronary artery branches with stenosis increased (P 0.05). The correlation analysis indicated that the ultrasound parameter of carotid atherosclerosis has a significant positive relation with the LVEDD, LVESD, ET-1, and vWF levels (P 0.05) and a negative relation with the LVEF and NO levels (P 0.05). Conclusion: The ultrasound parameter of carotid atherosclerosis, cardiac function, and endothelial function can be used for the early diagnosis of coronary heart disease.
机译：目的：本研究旨在发现颈动脉粥样硬化超声参数与冠心病患者心脏和内皮功能之间的关系。方法：将150例冠状动脉疾病患者分为单分支组（一种冠状动脉，具有狭窄曲率为50％），双分支组（具有狭窄曲率的两种冠状动脉，50％）和多分支基于每个患者的冠状动脉狭窄的严重程度，组（具有狭窄曲率的多冠状动脉＆ 50％）。与此同时，招募了50名入住医院进行常规健康检查的健康志愿者作为对照组。该研究测试了每组所有受试者的颈动脉动脉粥样硬化的超声参数[常见的颈动脉硬化（β），颈动脉顺应性（AC），弹性系数（EP），脉搏波传导速度（PWVβ）]，包括左心室舒张内直径（LVEDD），左心室喷射级分（LVEF）和内皮函数参数[内皮素-1（ET-1），von WILLEBRAND系数（VWF）和一氧化氮（NO）]。结果：该研究发现，冠状动脉疾病患者的β，AC，EP，PWVβ，LVEDD，LVESD，ET-1和VWF水平均高于对照组的相应水平（P <0.05）。随着冠状动脉分支的数量增加，值增加（P <0.05）。冠状动脉疾病的LVEF和NO患者低于对照组（P <0.05）。随着冠状动脉分支的狭窄增加（P <0.05），LVEF和NO率下降（P <0.05）。相关性分析表明，颈动脉粥样硬化的超声参数与Lvedd，Lversd，ET-1和VWF水平具有显着的阳性关系（P <0.05）和与LVEF和NO水平的阴性关系（P <0.05 ）。结论：颈动脉粥样硬化，心功能和内皮功能的超声参数可用于冠心病的早期诊断。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号