JC virus granule cell neuronopathy associated with Ruxolitinib: A case report and review of the literature

Kentaro Nakayama; Masataka Nakamura; Akiko Konishi; Satoshi Kaneko; Kazuo Nakamichi; Masayuki Saijo; Yusuke Yakushiji; Hirofumi Kusaka

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JC virus granule cell neuronopathy associated with Ruxolitinib: A case report and review of the literature

机译：JC病毒颗粒细胞神经病与Raxolitinib相关的神经病：一个案例报告和对文献的审查

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?We report here a case of JC virus granule cell neuronopathy associated with Ruxolitinib

?It is worthwhile considering the possibility of JCV-GCN in myelofibrosis patients receiving ruxiolitinib, who present with progressive cerebellar symptoms and cerebellar atrophy.

?Combination therapy using mefloquine and mirtazapine may be an effective treatment.

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亮点

？我们在此报告了与ruxolitinib相关的JC病毒颗粒细胞神经病病例

？考虑到JCV-GCN的可能性是值得的在接受ruxiolitinib的骨髓纤维病患者中，患有渐进的小脑症状和小脑萎缩。

？使用mefloquine和mirtazapine的组合治疗可能是有效的治疗方法。

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《eNeurologicalSci》 |2020年第a期|共3页
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Kentaro Nakayama; Masataka Nakamura; Akiko Konishi; Satoshi Kaneko; Kazuo Nakamichi; Masayuki Saijo; Yusuke Yakushiji; Hirofumi Kusaka;
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Progressive multifocal leukoencephalopathyGranule cell neuronopthyJC virusMyelofibrosisRuxolitinib;

机译：进步多灶性白血病疗法肠道肠道细胞神经元症患者毒蕈myelofibrysruxolitinib;
入库时间 2022-08-19 02:20:13

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1. Heterogeneous imaging characteristics of JC virus granule cell neuronopathy (GCN): a case series and review of the literature [J] . Wijburg Martijn T., van Oosten Bob W., Murk Jean-Luc, Journal of neurology . 2015,第1期

机译：JC病毒颗粒细胞神经病（GCN）的异相成像特征：病例系列和文献综述
2. JC virus granular neuronopathy and rhombencephalic progressive multifocal leukoencephalopathy: Case report and review of the literature [J] . KeithJ., BilbaoJ., BaskindR. Neuropathology: official journal of the Japanese Society of Neuropathology . 2012,第3期

机译：JC病毒颗粒神经病和菱形脑进行性多灶性白质脑病：病例报告和文献复习
3. JC Virus Granule Cell Neuronopathy and Lymphoma [J] . Alexis Demas, Omar Bennani, Anne Vandendriessche, Open Forum Infectious Diseases . 2018,第6期

机译：JC病毒颗粒细胞神经病和淋巴瘤
4. Assessing Review Reports of Scientific Articles: A Literature Review [C] . Amanda Sizo, Adriano Lino, álvaro Rocha World Conference on Information Systems and Technologies . 2018

机译：评估科学论文的审查报告：文献综述
5. The association between the polyomaviruses, JC virus, Bk virus, and simian virus 40, and human brain tumors. [D] . Rollison, Dana Elise Maher. 2003

机译：多瘤病毒，JC病毒，Bk病毒和猿猴病毒40与人脑肿瘤之间的关联。
6. JC virus granule cell neuronopathy associated with Ruxolitinib: A case report and review of the literature [O] . Kentaro Nakayama, Masataka Nakamura, Akiko Konishi, 2020

机译：JC病毒颗粒细胞神经病与Raxolitinib相关的内蒙古病症：案例报告和对文献的审查
7. Progressive multifocal leukoencephalopathy with bilateral middle cerebellar peduncle lesions confirmed by repeated CSF-JC virus tests and coexistence of JC virus granule cell neuronopathy. Report of a case [O] . Daisuke Ito, Keizo Yasui, Yasuhiro Hasegawa, 2016

机译：通过反复CSF-JC病毒测试和JC病毒颗粒细胞神经病的反复CSF-JC病毒试验证实，具有双侧中间小脑血管病变的进展多焦白血病病变。案子

JC virus granule cell neuronopathy associated with Ruxolitinib: A case report and review of the literature

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