Estimation of body surface area in neonates, infants, and children using body weight alone

摘要

BackgroundThe aim of this study was to use Body Surface Area (BSA) data calculated with the Mosteller equation to test potential new equations that estimate BSA using Body Weight (BW) alone in children aged 0–18 years.Mosteller’s equation, the golden standard at our hospital, was used to calculate the BSA in infants and children aged 0–18 years using BW and height data from 27,440 hospital visits by 20,635 patients over one year.MethodsThe best fit of three nonlinear regression equations (third-order polynomial, Meeh-type, and modified Boyd self-adjusting-type) to a plot of the calculated Mosteller BSA values versus BW was then investigated. The correlation between the BSA values estimated by these equations and the Mosteller BSA values was established by the Spearman rank correlation test. Bias and precision were evaluated as outlined by Sheiner and Beal. Measured and estimated BSA values were compared using the Eksborg plot.ResultsThe estimated BSA values from all three equations and the BSA values from the Mosteller equation were closely correlated (P?