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Moraxella nonliquefaciens septic arthritis in an immunocompetent child: A case report

机译: moraxella nonliquaciens 免疫活性子女的静脉曲张炎:案例报告

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A 2-year-old, previously healthy, male presented with an insidious history of intermittent left knee pain and edema who had been evaluated in the emergency department on multiple occasions with unremarkable imaging and normal laboratory results. On the day of presentation, he had mild edema of the left knee and inability to bear weight. Synovial fluid analysis showed an elevated white cell count with neutrophil predominance and mildly elevated inflammatory markers, consistent with septic arthritis. He underwent knee arthrotomy with irrigation and debridement and was initiated on broad spectrum antibiotics. Cultures were negative, polymerase chain reaction for MRSA andKingella kingaewere negative. He was started on a fifth-generation cephalosporin with resolution of symptoms, marked clinical improvement and normalization of inflammatory markers. The identification of the etiologic agent was possible due to detection of bacterial 16S rRNA gene amplification by PCR forMoraxella nonliquefaciensin the synovial fluid. He completed a course of 3 weeks of parenteral antibiotics at home with full recovery.
机译:一个2岁的,以前健康的男性呈现出一个阴险的间歇性左膝盖疼痛和水肿,他们在急诊部门在急诊部门评估了不起眼的成像和正常的实验室结果。在介绍当天,他的左膝部温和的水肿和无法承受重量。滑膜流体分析显示,具有中性粒细胞优势和轻度升高的炎症标记物的白色细胞计数升高,与化学关节炎一致。他接受了膝关节关节术,随着灌溉和清创,并在广谱抗生素上启动。培养物是阴性,聚合酶链反应,MRSA和Kingella Kingaewere阴性。他开始于第五代头孢孢菌素,分辨症状,标志着临床改善和炎症标志物的标准化。由于PCR Formoraxella Nonliquefacensins滑膜液的检测,可能由于检测到细菌16s rRNA基因扩增,因此可以鉴定病因。他在家里完成了3周的肠外抗生素的课程,全面恢复。

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