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首页> 外文期刊>Journal of the Formosan Medical Association =: Taiwan yi zhi >Efficacy and safety of balloon pulmonary angioplasty in patients with inoperable chronic thromboembolic pulmonary hypertension
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Efficacy and safety of balloon pulmonary angioplasty in patients with inoperable chronic thromboembolic pulmonary hypertension

机译:慢性血栓栓塞肺动脉高压术患者气球肺血管成形术的疗效和安全性

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BackgroundData on the efficacy and safety of balloon pulmonary angioplasty (BPA) in Taiwanese patients with chronic thromboembolic pulmonary hypertension (CTEPH) are lacking. In this study, we evaluated the effects of BPA on clinical parameters including hemodynamics, echocardiography and functional status in patients with inoperable CTEPH in Taiwan.MethodsWe retrospectively collected the clinical data of inoperable CTEPH patients who underwent ≥3 BPA sessions. Pulmonary hemodynamic parameters of right heart catheterization, echocardiography, 6-min walk distance and World Health Organization (WHO) functional class were collected and analyzed before and after BPA treatment.ResultsA total of 59 BPA sessions were performed in 13 inoperable CTEPH patients. No periprocedural deaths or major complications requiring tracheal intubation with mechanical ventilation occurred. WHO functional class significantly improved in all 13 patients (P?
机译:BackgroundData缺乏慢性血栓栓塞肺动脉高压(CTEPH)台湾肺血管成形术(BPA)的疗效和安全性。在这项研究中,我们评估了BPA对台湾无法操作的CTEPH患者患者临床参数对临床参数的影响。一点回顾性地收集了≥3个BPA会话的Inoperal CTEPH患者的临床数据。在BPA治疗之前和之后,收集和分析了右心导管,超声心动图,6分钟步行距离和世界卫生组织(世卫组织)功能阶层的肺血流动力学参数。在13名不可操作的CTEPH患者中进行了59个BPA会话的总共59个BPA会话。没有发生具有机械通气气管插管的霸王性死亡或主要并发症。谁在所有13名患者(P?<0.001)中的功能阶级显着改善,6分钟步行距离从344?±147到450?±120?m?(p?= 0.014)。另外,N末端促脑利钠肽的血浆水平显着降低(P?= 0.007)。 ≥3个BPA会话后,11名患者提供血液动力学数据。平均肺动脉压力和肺血管阻力均显着降低44.6?±11.7?mmHg至32.6?±5.1?mmhg(p?= 0.005)和745?±389?dyn·s·cm?5到366? ±120?dyn·s·cm?5(p?= 0.002)。心输出也从3.69增加到3.69?±1.12?l / min至4.33?±0.94?l / min(p?= 0.021).ConclusionBPA改善了在没有主要的围栏并发症的患者中无法操作的CTeph台湾患者患有临床症状和血液动力学数据。

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